A tumor cell membrane-coated self-amplified nanosystem as a nanovaccine to boost the therapeutic effect of anti-PD-L1 antibody

A tumor cell membrane-coated self-amplified nanosystem as a nanovaccine to boost the therapeutic effect of anti-PD-L1 antibody

To improve the response rate of immune checkpoint inhibitors such as anti-PD-L1 antibody in immunosuppressive cancers like triple-negative breast cancer (TNBC), induction of immunogenic cell death (ICD) at tumor sites can increase the antigenicity and adjuvanticity to activate the immune microenviro...

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Bibliographic Details
Main Authors: Zhilin Li, Hao Cai, Zhiqian Li, Long Ren, Xuelei Ma, Hongyan Zhu, Qiyong Gong, Hu Zhang, Zhongwei Gu, Kui Luo
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-03-01
Series:Bioactive Materials
Subjects:
Cell membrane
Biomimetic nanosystem
Immunogenic cell death
Immunotherapy
anti-PD-L1 antibody
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22003711

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http://www.sciencedirect.com/science/article/pii/S2452199X22003711

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