The rate of microtubule breaking increases exponentially with curvature

Abstract Microtubules, cylindrical assemblies of tubulin proteins with a 25 nm diameter and micrometer lengths, are a central part of the cytoskeleton and also serve as building blocks for nanobiodevices. Microtubule breaking can result from the activity of severing enzymes and mechanical stress. Br...

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Bibliographic Details
Main Authors: Stanislav Tsitkov, Juan B. Rodriguez, Neda M. Bassir Kazeruni, May Sweet, Takahiro Nitta, Henry Hess
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24912-0