Development of a novel definitive scoring system for an enteral feed-only model of necrotizing enterocolitis in piglets

IntroductionNecrotizing enterocolitis (NEC) is a complex inflammatory disorder of the human intestine that most often occurs in premature newborns. Animal models of NEC typically use mice or rats; however, pigs have emerged as a viable alternative given their similar size, intestinal development, an...

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Main Authors: Mecklin V. Ragan, Samantha J. Wala, Nitin Sajankila, Audrey F. Duff, Yijie Wang, Samuel G. Volpe, Ameer Al-Hadidi, Zachary Dumbauld, Nanditha Purayil, Joseph Wickham, Miriam R. Conces, Belgacem Mihi, Steven D. Goodman, Michael T. Bailey, Gail E. Besner
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1126552/full