Coupling imaging mass cytometry with Alcian blue histochemical staining for a single-slide approach

Coupling imaging mass cytometry with Alcian blue histochemical staining for a single-slide approach

Imaging mass cytometry (IMC) is a metal mass spectrometry-based method allowing highly multiplex immunophenotyping of cells within tissue samples. However, some limitations of IMC are its 1-µm resolution and its time and costs of analysis limiting respectively the detailed histopathological analysis...

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Bibliographic Details
Main Authors: Patrice Hemon, Danivanh Ben-Guigui, Margaux Geier, Marine Castillon, Corentin Paranthoen, Jacques-Olivier Pers, Marion Le Rochais, Arnaud Uguen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
imaging mass cytometry
Alcian blue
digital pathology
fixative
histochemical staining
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1379154/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1379154/full

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