Rutaecarpine suppresses atherosclerosis in ApoE−/− mice through upregulating ABCA1 and SR-BI within RCT[S]

Rutaecarpine suppresses atherosclerosis in ApoE−/− mice through upregulating ABCA1 and SR-BI within RCT[S]

ABCA1 and scavenger receptor class B type I (SR-BI)/CD36 and lysosomal integral membrane protein II analogous 1 (CLA-1) are the key transporter and receptor in reverse cholesterol transport (RCT). Increasing the expression level of ABCA1 and SR-BI/CLA-1 is antiatherogenic. The aim of the study was t...

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Bibliographic Details
Main Authors: Yanni Xu, Qi Liu, Yang Xu, Chang Liu, Xiao Wang, Xiaobo He, Ningyu Zhu, Jikai Liu, Yexiang Wu, Yongzhen Li, Ni Li, Tingting Feng, Fangfang Lai, Murui Zhang, Bin Hong, Jian-Dong Jiang, Shuyi Si
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein E deficient
ATP binding cassette transporter A1
scavenger receptor class B type I
reverse cholesterol transport
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752035327X

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http://www.sciencedirect.com/science/article/pii/S002222752035327X

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