NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer

NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer

Abstract The emergence of resistance to systemic therapies in pancreatic ductal adenocarcinoma (PDAC) is still a major obstacle in clinical practice. Both, constitutive and inducible NF-κB activity are known as key players in this context. To identify differentially expressed and TRAIL resistance me...

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Main Authors: Claudia Geismann, Charlotte Hauser, Frauke Grohmann, Christian Schneeweis, Nico Bölter, Jan-Paul Gundlach, Günter Schneider, Christoph Röcken, Christian Meinhardt, Heiner Schäfer, Stefan Schreiber, Alexander Arlt
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05535-9

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https://doi.org/10.1038/s41419-022-05535-9

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