Parthenolide as Cooperating Agent for Anti-Cancer Treatment of Various Malignancies
Primary and acquired resistance of cancer to therapy is often associated with activation of nuclear factor kappa B (NF-κB). Parthenolide (PN) has been shown to inhibit NF-κB signaling and other pro-survival signaling pathways, induce apoptosis and reduce a subpopulation of cancer stem-like cells in...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/13/8/194 |