Exploring the Effects of Process Parameters during W/O/W Emulsion Preparation and Supercritical Fluid Extraction on the Protein Encapsulation and Release Properties of PLGA Microspheres

Exploring the Effects of Process Parameters during W/O/W Emulsion Preparation and Supercritical Fluid Extraction on the Protein Encapsulation and Release Properties of PLGA Microspheres

In this study, protein-loaded poly(lactic-co-glycolic acid) (PLGA) microspheres were prepared via supercritical fluid extraction of emulsion (SFEE) technology. To understand the correlation between process parameters and the main quality characteristics of PLGA microspheres, a comprehensive prior st...

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Bibliographic Details
Main Author: Heejun Park
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pharmaceutics
Subjects:
supercritical fluid extraction of emulsions
PLGA microspheres
encapsulation efficiency
initial burst release
bovine serum albumin
Online Access:https://www.mdpi.com/1999-4923/16/3/302

Internet

https://www.mdpi.com/1999-4923/16/3/302

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