Atlas of regulated target genes of transcription factors (ART-TF) in human ES cells

Atlas of regulated target genes of transcription factors (ART-TF) in human ES cells

Abstract Background Transcription factors (TFs) play central roles in maintaining “stemness” of embryonic stem (ES) cells and their differentiation into several hundreds of adult cell types. The regulatory competence of TFs is routinely assessed by detecting target genes to which they bind. However,...

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Bibliographic Details
Main Authors: Alexei A. Sharov, Yuhki Nakatake, Weidong Wang
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Bioinformatics
Subjects:
Genome binding of transcription factors
Induction of transcription factors
Regulated target genes
Parametric analysis of gene expression
Embryonic stem cells
Enhancer-promoter loop
Online Access:https://doi.org/10.1186/s12859-022-04924-3

Internet

https://doi.org/10.1186/s12859-022-04924-3

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