Human Menstrual Blood-Derived Stem Cells Protect against Tacrolimus-Induced Islet Dysfunction via Cystathionine β-Synthase Mediated IL-6/STAT3 Inactivation

Human Menstrual Blood-Derived Stem Cells Protect against Tacrolimus-Induced Islet Dysfunction via Cystathionine β-Synthase Mediated IL-6/STAT3 Inactivation

Diabetes imposes a huge burden worldwide. Islet transplantation is an alternative therapy for diabetes. However, tacrolimus, a kind of immunosuppressant after organ transplantation, is closely related to post-transplant diabetes mellitus. Mesenchymal stem cells (MSCs) have attracted interest for the...

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Bibliographic Details
Main Authors: Jiamin Fu, Qi Zhang, Ning Zhang, Sining Zhou, Yangxin Fang, Yifei Li, Li Yuan, Lijun Chen, Charlie Xiang
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Biomolecules
Subjects:
mesenchymal stem cells
diabetes
apoptosis
transplantation
Online Access:https://www.mdpi.com/2218-273X/14/6/671

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https://www.mdpi.com/2218-273X/14/6/671

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