DNA damage alters EGFR signaling and reprograms cellular response via Mre-11

Abstract To combat the various DNA lesions and their harmful effects, cells have evolved different strategies, collectively referred as DNA damage response (DDR). The DDR largely relies on intranuclear protein networks, which sense DNA lesions, recruit DNA repair enzymes, and coordinates several asp...

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Bibliographic Details
Main Authors: Yael Volman, Ruth Hefetz, Eithan Galun, Jacob Rachmilewitz
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09779-5