Matrix vesicles promote bone repair after a femoral bone defect in mice.

Matrix vesicles (MtVs) are one of the extracellular vesicles (EVs) secreted by osteoblasts. Although MtVs have a classically-defined function as an initiator of ossification and recent findings suggest a role for MtVs in the regulation of bone cell biology, the effects of MtVs on bone repair remain...

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Bibliographic Details
Main Authors: Yuya Mizukami, Naoyuki Kawao, Yoshimasa Takafuji, Takashi Ohira, Kiyotaka Okada, Jun-Ichiro Jo, Yasuhiko Tabata, Hiroshi Kaji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0284258