Astrocytes of the optic nerve exhibit a region-specific and temporally distinct response to elevated intraocular pressure

Abstract Background The optic nerve is an important tissue in glaucoma and the unmyelinated nerve head region remains an important site of many early neurodegenerative changes. In both humans and mice, astrocytes constitute the major glial cell type in the region, and in glaucoma they become reactiv...

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Bibliographic Details
Main Authors: Arpan G. Mazumder, Amélie M. Julé, Daniel Sun
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-023-00658-9