CD70 in Thymic Squamous Cell Carcinoma: Potential Diagnostic Markers and Immunotherapeutic Targets

CD70 in Thymic Squamous Cell Carcinoma: Potential Diagnostic Markers and Immunotherapeutic Targets

CD70 – a ligand protein of CD27 on lymphocytes – is expressed in a large spectrum of malignancies. It is an attractive target for antibody-based therapy and several clinical trials are currently being conducted. However, there is no evidence regarding the expression of CD70 and its relationship with...

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Bibliographic Details
Main Authors: Jumpei Kashima, Tsunekazu Hishima, Yusuke Okuma, Hirotoshi Horio, Masumi Ogawa, Yukiko Hayashi, Shin-ichiro Horiguchi, Toru Motoi, Tetsuo Ushiku, Masashi Fukayama
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
thymic carcinoma
CD70
CD27
immunohistochemistry
tumor-infiltrating lymphocyte
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.808396/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.808396/full

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