Deep brain stimulation in the lateral habenula reverses local neuronal hyperactivity and ameliorates depression-like behaviors in rats

Deep brain stimulation in the lateral habenula reverses local neuronal hyperactivity and ameliorates depression-like behaviors in rats

Deep brain stimulation (DBS) is a promising therapy for treatment-resistant depression, while mechanisms underlying its therapeutic effects remain poorly defined. Increasing evidence has revealed an intimate association between the lateral habenula (LHb) and major depression, and suggests that the L...

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Bibliographic Details
Main Authors: Yuqi Zhang, Longyu Ma, Xueying Zhang, Lupeng Yue, Jiaxin Wang, Jie Zheng, Shuang Cui, Feng-Yu Liu, Zhiyan Wang, You Wan, Ming Yi
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Neurobiology of Disease
Subjects:
Lateral habenula
Depression
Deep brain stimulation
In vivo recording
Burst firing
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123000839

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http://www.sciencedirect.com/science/article/pii/S0969996123000839

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