Mitochondrial Open Reading Frame of the 12S rRNA Type-c: Potential Therapeutic Candidate in Retinal Diseases

Mitochondrial Open Reading Frame of the 12S rRNA Type-c: Potential Therapeutic Candidate in Retinal Diseases

Mitochondrial open reading frame of the 12S rRNA type-c (MOTS-c) is the most unearthed peptide encoded by mitochondrial DNA (mtDNA). It is an important regulator of the nuclear genome during times of stress because it promotes an adaptive stress response to maintain cellular homeostasis. Identifying...

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Bibliographic Details
Main Authors: Zahra Mohtashami, Mithalesh Kumar Singh, Farid Thomaz Neto, Nasim Salimiaghdam, Hossein Hasanpour, M. Cristina Kenney
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antioxidants
Subjects:
MOTS-c
mitochondrial dysfunction
glaucoma
diabetic retinopathy
age-related macular degeneration
Online Access:https://www.mdpi.com/2076-3921/12/2/518

Internet

https://www.mdpi.com/2076-3921/12/2/518

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