Sequential use of midazolam and dexmedetomidine for long-term sedation may reduce weaning time in selected critically ill, mechanically ventilated patients: a randomized controlled study

Abstract Background Current sedatives have different side effects in long-term sedation. The sequential use of midazolam and dexmedetomidine for prolonged sedation may have distinct advantages. We aimed to evaluate the efficacy and safety of the sequential use of midazolam and either dexmedetomidine...

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Bibliographic Details
Main Authors: Yongfang Zhou, Jie Yang, Bo Wang, Peng Wang, Zhen Wang, Yunqin Yang, Guopeng Liang, Xiaorong jing, Xiaodong Jin, Zhongwei Zhang, Yiyun Deng, Chenggong Hu, Xuelian Liao, Wanhong Yin, Zhihong Tang, Yongming Tian, Liyuan Tao, Yan Kang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s13054-022-03967-5