The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil
<p>Abstract</p> <p>Background</p> <p>Metabolic reprogramming resulting in enhanced glycolysis is a phenotypic trait of cancer cells, which is imposed by the tumor microenvironment and is linked to the down-regulation of the catalytic subunit of the mitochondrial H<su...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-02-01
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Series: | Journal of Translational Medicine |
Online Access: | http://www.translational-medicine.com/content/9/1/19 |