Angiotensin‐Converting Enzyme 3 (ACE3) Protects Against Pressure Overload‐Induced Cardiac Hypertrophy

Angiotensin‐Converting Enzyme 3 (ACE3) Protects Against Pressure Overload‐Induced Cardiac Hypertrophy

BackgroundAngiotensin‐converting enzyme 3 (ACE3) is a recently defined homolog of ACE. However, the pathophysiological function of ACE3 is largely unknown. Here, we aim to explore the role of ACE3 in pathological cardiac hypertrophy. Methods and ResultsNeonatal rat cardiomyocytes (NRCMs) with gain a...

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Bibliographic Details
Main Authors: Chang‐Jiang Yu, Liang‐Liang Tang, Chen Liang, Xiao Chen, Shu‐Ying Song, Xiao‐Qing Ding, Kun‐Yu Zhang, Bin‐Lin Song, Dan Zhao, Xue‐Yong Zhu, Hong‐Liang Li, Zhi‐Ren Zhang
Format: Article
Language:English
Published: Wiley 2016-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
angiotensin‐converting enzyme 3
cardiac hypertrophy
ERK1/2
MEK1/2
signaling pathway
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.115.002680

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.115.002680

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