Principles of mRNA targeting via the Arabidopsis m6A-binding protein ECT2

Principles of mRNA targeting via the Arabidopsis m6A-binding protein ECT2

Specific recognition of N6-methyladenosine (m6A) in mRNA by RNA-binding proteins containing a YT521-B homology (YTH) domain is important in eukaryotic gene regulation. The Arabidopsis YTH domain protein ECT2 is thought to bind to mRNA at URU(m6A)Y sites, yet RR(m6A)CH is the canonical m6A consensus...

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Bibliographic Details
Main Authors: Laura Arribas-Hernández, Sarah Rennie, Tino Köster, Carlotta Porcelli, Martin Lewinski, Dorothee Staiger, Robin Andersson, Peter Brodersen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
m6A
ECT2
iCLIP
hyperTRIBE
RRACH
motif
Online Access:https://elifesciences.org/articles/72375

Internet

https://elifesciences.org/articles/72375

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