Complex dispersions of poloxamers and mesoporous carriers with ibrutinib

Complex dispersions of poloxamers and mesoporous carriers with ibrutinib

Ibrutinib is an anticancer drug, a Bruton's tyrosine kinase inhibitor with poor solubility in aqueous media. This study reports on the study of the effectiveness of mesoporous carriers based on magnesium aluminometasilicate and poloxamers to improve the solubility and bioavailability of ibrutin...

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Bibliographic Details
Main Authors: Igor A. Dain, Sergey A. Zolotov, Natalia B. Demina, Anna S. Zolotova, Grigorii A. Buzanov, Vasilii M. Retivov, Yevgenii S. Ponomaryov
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:OpenNano
Subjects:
Ibrutinib
Mesoporous carrier
Dissolution testing
X-ray powder diffraction
Poloxamer
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952022000354

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http://www.sciencedirect.com/science/article/pii/S2352952022000354

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