The role of PD-1/PD-L1 axis in idiopathic pulmonary fibrosis: Friend or foe?

The role of PD-1/PD-L1 axis in idiopathic pulmonary fibrosis: Friend or foe?

Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with a bleak prognosis. Mounting evidence suggests that IPF shares bio-molecular similarities with lung cancer. Given the deep understanding of the programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway...

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Bibliographic Details
Main Authors: Aimin Jiang, Na Liu, Jingjing Wang, Xiaoqiang Zheng, Mengdi Ren, Wei Zhang, Yu Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
PD-1
PD-L1
idiopathic pulmonary fibrosis
profibrotic role
immunomodulatory role
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1022228/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1022228/full

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