Low circulatory levels of total cholesterol, HDL-C and LDL-C are associated with death of patients with sepsis and critical illness: systematic review, meta-analysis, and perspective of observational studiesResearch in context

Low circulatory levels of total cholesterol, HDL-C and LDL-C are associated with death of patients with sepsis and critical illness: systematic review, meta-analysis, and perspective of observational studiesResearch in context

Summary: Background: Mechanistic studies have established a biological role of sterol metabolism in infection and immunity with clinical data linking deranged cholesterol metabolism during sepsis with poorer outcomes. In this systematic review we assess the relationship between biomarkers of choles...

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Bibliographic Details
Main Authors: Rory Taylor, Chengyuan Zhang, Deslit George, Sarah Kotecha, Mariam Abdelghaffar, Thorsten Forster, Patricia Dos Santos Rodrigues, Alexander C. Reisinger, Daniel White, Fergus Hamilton, W. John Watkins, David M. Griffith, Peter Ghazal
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:EBioMedicine
Subjects:
Sepsis
Critical illness
Lipids
Cholesterol
Immunometabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424000161

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http://www.sciencedirect.com/science/article/pii/S2352396424000161

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