A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels

A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels

The genetic determinants of low-density lipoprotein cholesterol (LDL-C) levels in blood have been predominantly explored in European populations and remain poorly understood in Middle Eastern populations. We investigated the genetic architecture of LDL-C variation in Qatar by conducting a genome-wid...

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Bibliographic Details
Main Authors: Umm-Kulthum Ismail Umlai, Salman M. Toor, Yasser A. Al-Sarraj, Shaban Mohammed, Moza S.H. Al Hail, Ehsan Ullah, Khalid Kunji, Ayman El-Menyar, Mohammed Gomaa, Amin Jayyousi, Mohamad Saad, Nadeem Qureshi, Jassim M. Al Suwaidi, Omar M.E. Albagha
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Lipid Research
Subjects:
genomics
LDL
cholesterol
dyslipidemias
atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227525000124

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http://www.sciencedirect.com/science/article/pii/S0022227525000124

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