Caenorhabditis elegans: a model to investigate oxidative stress and metal dyshomeostasis in Parkinson’s disease

Parkinson’s disease is characterized by progressive motor impairment attributed to progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Additional clinical manifestations include non-motor symptoms such as insomnia, depression, psychosis and cognitive impairment. Parkinson...

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Bibliographic Details
Main Authors: Patricia Mugure Chege, Gawain eMccoll
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00089/full