Loss of maternal CTCF is associated with peri-implantation lethality of Ctcf null embryos.

CTCF is a highly conserved, multifunctional zinc finger protein involved in critical aspects of gene regulation including transcription regulation, chromatin insulation, genomic imprinting, X-chromosome inactivation, and higher order chromatin organization. Such multifunctional properties of CTCF su...

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Bibliographic Details
Main Authors: James M Moore, Natalia A Rabaia, Leslie E Smith, Sara Fagerlie, Kay Gurley, Dmitry Loukinov, Christine M Disteche, Steven J Collins, Christopher J Kemp, Victor V Lobanenkov, Galina N Filippova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3332108?pdf=render