LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway

LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway

Objective: Abscisic acid (ABA) is a plant hormone also present and active in animals. In mammals, ABA regulates blood glucose levels by stimulating insulin-independent glucose uptake and metabolism in adipocytes and myocytes through its receptor LANCL2. The objective of this study was to investigate...

Full description

Bibliographic Details
Main Authors: Sonia Spinelli, Giulia Begani, Lucrezia Guida, Mirko Magnone, Denise Galante, Cristina D'Arrigo, Claudia Scotti, Luisa Iamele, Hugo De Jonge, Elena Zocchi, Laura Sturla
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Molecular Metabolism
Subjects:
LANCL1
Abscisic acid
Glucose transporters
UCP3
Sarcolipin
Cell respiration
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001083

Internet

http://www.sciencedirect.com/science/article/pii/S2212877821001083

Similar Items