Transcriptome and TCR Repertoire Measurements of CXCR3+ T Follicular Helper Cells Within HIV-Infected Human Lymph Nodes

Transcriptome and TCR Repertoire Measurements of CXCR3+ T Follicular Helper Cells Within HIV-Infected Human Lymph Nodes

Follicular-helper T cells (TFH) are an essential arm of the adaptive immune system. Although TFH were first discovered through their ability to contribute to antibody affinity maturation through co-stimulatory interactions with B cells, new light has been shed on their ability to remain a complex an...

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Bibliographic Details
Main Authors: Chenfeng He, Michael J. Malone, Ben S. Wendel, Ke-Yue Ma, Daniel Del Alcazar, David B. Weiner, Philip L. De Jager, Perla M. Del Río-Estrada, Yuria Ablanedo-Terrazas, Gustavo Reyes-Terán, Laura F. Su, Ning Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
CXCR3
follicular-helper T cells (TFH)
TCR repertoire
RNA-seq
HIV
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.859070/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.859070/full

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