Effect of <italic toggle="yes">tcdR</italic> Mutation on Sporulation in the Epidemic <named-content content-type="genus-species">Clostridium difficile</named-content> Strain R20291

Effect of <italic toggle="yes">tcdR</italic> Mutation on Sporulation in the Epidemic <named-content content-type="genus-species">Clostridium difficile</named-content> Strain R20291

ABSTRACT Clostridium difficile is an important nosocomial pathogen and the leading cause of hospital-acquired diarrhea. Antibiotic use is the primary risk factor for the development of C. difficile-associated disease because it disrupts normally protective gut flora and enables C. difficile to colon...

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Bibliographic Details
Main Authors: Brintha P. Girinathan, Marc Monot, Daniel Boyle, Kathleen N. McAllister, Joseph A. Sorg, Bruno Dupuy, Revathi Govind
Format: Article
Language:English
Published: American Society for Microbiology 2017-02-01
Series:mSphere
Subjects:
Clostridium difficile
sporulation
toxin gene regulation
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00383-16

Internet

https://journals.asm.org/doi/10.1128/mSphere.00383-16

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