Synthesis of Mixed Dinucleotides by Mechanochemistry

We report the synthesis of vitamin B1, B2, and B3 derived nucleotides and dinucleotides generated either through mechanochemical or solution phase chemistry. Under the explored conditions, adenosine and thiamine proved to be particularly amenable to milling conditions. Following optimization of the...

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Bibliographic Details
Main Authors: Faisal Hayat, Mikhail V. Makarov, Luxene Belfleur, Marie E. Migaud
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/10/3229