Structural diversity of oligomeric β-propellers with different numbers of identical blades

Structural diversity of oligomeric β-propellers with different numbers of identical blades

β-Propellers arise through the amplification of a supersecondary structure element called a blade. This process produces toroids of between four and twelve repeats, which are almost always arranged sequentially in a single polypeptide chain. We found that new propellers evolve continuously by amplif...

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Bibliographic Details
Main Authors: Evgenia Afanasieva, Indronil Chaudhuri, Jörg Martin, Eva Hertle, Astrid Ursinus, Vikram Alva, Marcus D Hartmann, Andrei N Lupas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
beta-propellers
oligomeric proteins
protein design
protein evolution
sequence repeat amplificati
Online Access:https://elifesciences.org/articles/49853

Internet

https://elifesciences.org/articles/49853

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