Self-assembled nanoparticle-enzyme aggregates enhance functional protein production in pure transcription-translation systems.

Self-assembled nanoparticle-enzyme aggregates enhance functional protein production in pure transcription-translation systems.

Cell-free protein synthesis systems (CFPS) utilize cellular transcription and translation (TX-TL) machinery to synthesize proteins in vitro. These systems are useful for multiple applications including production of difficult proteins, as high-throughput tools for genetic circuit screening, and as s...

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Bibliographic Details
Main Authors: Meghna Thakur, Joyce C Breger, Kimihiro Susumu, Eunkeu Oh, Joseph R Spangler, Igor L Medintz, Scott A Walper, Gregory A Ellis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0265274

Internet

https://doi.org/10.1371/journal.pone.0265274

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