Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma

There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors demonstrate that ITGA7 is a potential functional marker of oesophageal cancer stem cells involved in the resistance to chemotherapy and metastasis through activation of FAK-mediated signalling.

Bibliographic Details
Main Authors: Xiao-Yan Ming, Li Fu, Li-Yi Zhang, Yan-Ru Qin, Ting-Ting Cao, Kwok Wah Chan, Stephanie Ma, Dan Xie, Xin-Yuan Guan
Format: Article
Language:English
Published: Nature Portfolio 2016-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13568