Binding of Glycerol to Human Galectin-7 Expands Stability and Modulates Its Functions

Binding of Glycerol to Human Galectin-7 Expands Stability and Modulates Its Functions

Glycerol is seen in biological systems as an intermediate in lipid metabolism. In recent years, glycerol has been reported to act as a chemical chaperone to correct the conformation of proteins. Here, we investigate the role of glycerol in galectin-7 (Gal-7). The thermal shift and CD assays showed t...

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Bibliographic Details
Main Authors: Yebing Liang, Yuxiang Wang, Xingyu Zhu, Jun Cai, Anqi Shi, Jing Huang, Qiuju Zhu, Yunlong Si
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
galectin-7
glycerol
stability
crystal structure
aquaporin-3
Online Access:https://www.mdpi.com/1422-0067/23/20/12318

Internet

https://www.mdpi.com/1422-0067/23/20/12318

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