SOX9 inactivation affects the proliferation and differentiation of human lung organoids

SOX9 inactivation affects the proliferation and differentiation of human lung organoids

Abstract Background The regulation of the transcription factor sex-determining region Y-box transcription factor 9 (SOX9) in lung development has been described in mouse, but the same principles apply to human lung development is unknown due to a lack of appropriate experimental approaches and model...

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Bibliographic Details
Main Authors: Lian Li, Jianqi Feng, Shanshan Zhao, Zhili Rong, Ying Lin
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Stem Cell Research & Therapy
Subjects:
Lung organoids
SOX9
CRISPR/Cas9
Proliferation
Differentiation
Online Access:https://doi.org/10.1186/s13287-021-02422-6

Internet

https://doi.org/10.1186/s13287-021-02422-6

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