Release of carbohydrates from sphingoglycolipid by osmium-catalyzed periodate oxidation followed by treatment with mild alkali

The carbohydrate moiety of sphingoglycolipid, after preliminary acetylation, can be released by periodate oxidation catalyzed by a trace amount of osmium tetroxide, followed by alkaline treatment.Cerebroside, lactosyl ceramide, hematoside, globoside, and gangliosides were degraded to yield, respecti...

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Bibliographic Details
Main Author: Sen-Itiroh Hakomori
Format: Article
Language:English
Published: Elsevier 1966-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520389586