Genomic Analysis Made It Possible to Identify Gene-Driver Alterations Covering the Time Window between Diagnosis of Neuroblastoma 4S and the Progression to Stage 4

Genomic Analysis Made It Possible to Identify Gene-Driver Alterations Covering the Time Window between Diagnosis of Neuroblastoma 4S and the Progression to Stage 4

Neuroblastoma (NB) is a tumor of the developing sympathetic nervous system. Despite recent advances in understanding the complexity of NB, the mechanisms that determine its regression or progression are still largely unknown. Stage 4S NB is characterized by a favorable course of disease and often by...

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Bibliographic Details
Main Authors: Marzia Ognibene, Patrizia De Marco, Stefano Parodi, Mariaclaudia Meli, Andrea Di Cataldo, Federico Zara, Annalisa Pezzolo
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
Neuroblastoma
stage 4S
tumor progression
array-comparative genomic hybridization
whole-exome sequencing
somatic copy number alterations
Online Access:https://www.mdpi.com/1422-0067/23/12/6513

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https://www.mdpi.com/1422-0067/23/12/6513

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