Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis

Septic cardiomyopathy is characterized by impaired contractive function with mitochondrial dysregulation. Songorine is a typical active C20-diterpene alkaloid from the lateral root of Aconitum carmichaelii, which has been used for the treatment of heart failure. This study investigated the protectiv...

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Bibliographic Details
Main Authors: Yi Li, Yu-Fan Feng, Xiao-Tian Liu, Yu-Chen Li, Hui-Min Zhu, Meng-Ru Sun, Ping Li, Baolin Liu, Hua Yang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309769