Ubiquitin C-Terminal Hydrolase L5 Plays an Essential Role in the Fly Innate Immune Defense against Bacterial Infection

Ubiquitin C-Terminal Hydrolase L5 Plays an Essential Role in the Fly Innate Immune Defense against Bacterial Infection

Background: Drosophila ubiquitin carboxy-terminal hydrolase L5 (Uch-L5) functions as a critical component of the 26S proteasome to mediate degradation of polyubiquitinated proteins. It was recently shown to modulate tissue/organ development by targeting the Smoothened protein in the hedgehog pathway...

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Bibliographic Details
Main Authors: Chao Zhang, Shikun Zhang, Fanrui Kong, Yihua Xiao, Kan She, Yiheng Jin, Jiashu Li, Abdul Qadeer, Xianrui Zheng, Shanming Ji, Yongzhi Hua
Format: Article
Language:English
Published: IMR Press 2023-11-01
Series:Frontiers in Bioscience-Landmark
Subjects:
uch-l5
imd signaling
innate immune response
drosophila melanogaster
Online Access:https://www.imrpress.com/journal/FBL/28/11/10.31083/j.fbl2811294

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https://www.imrpress.com/journal/FBL/28/11/10.31083/j.fbl2811294

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