Developing an Efficient and General Strategy for Immobilization of Small Molecules onto Microarrays Using Isocyanate Chemistry

Developing an Efficient and General Strategy for Immobilization of Small Molecules onto Microarrays Using Isocyanate Chemistry

Small-molecule microarray (SMM) is an effective platform for identifying lead compounds from large collections of small molecules in drug discovery, and efficient immobilization of molecular compounds is a pre-requisite for the success of such a platform. On an isocyanate functionalized surface, we...

Full description

Bibliographic Details
Main Authors: Chenggang Zhu, Xiangdong Zhu, James P. Landry, Zhaomeng Cui, Quanfu Li, Yongjun Dang, Lan Mi, Fengyun Zheng, Yiyan Fei
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Sensors
Subjects:
high-throughput screening
small-molecule microarrays
surface functionalization
label-free optical biosensor
Online Access:http://www.mdpi.com/1424-8220/16/3/378

Internet

http://www.mdpi.com/1424-8220/16/3/378

Similar Items