The CaSR in Pathogenesis of Breast Cancer: A New Target for Early Stage Bone Metastases

The CaSR in Pathogenesis of Breast Cancer: A New Target for Early Stage Bone Metastases

The Ca2+-sensing receptor (CaSR) is a class-C G protein-coupled receptor which plays a pivotal role in calciotropic processes, primarily in regulating parathyroid hormone secretion to maintain systemic calcium homeostasis. Among its non-calciotropic roles, where the CaSR sits at the intersection of...

Full description

Bibliographic Details
Main Authors: Souvik Das, Philippe Clézardin, Said Kamel, Michel Brazier, Romuald Mentaverri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
CaSR
calcium-sensing receptor
breast cancer
mammary gland
bone metastasis
calcilytics
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00069/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00069/full

Similar Items