Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages

<p>Abstract</p> <p>Background</p> <p>Although HIV can infect several cellular subsets, such as CD4<sup>+ </sup>T lymphocytes and macrophages, it remains unclear whether an HIV infection in macrophages supports cytotoxic T lymphocyte (CTL) escape. Here, we te...

ver descrição completa

Detalhes bibliográficos
Main Authors: Suzu Shinya, Hassan Ranya, Hasan Zafrul, Mwimanzi Philip, Takiguchi Masafumi, Ueno Takamasa
Formato: Artigo
Idioma:English
Publicado em: BMC 2011-06-01
Colecção:Retrovirology
Acesso em linha:http://www.retrovirology.com/content/8/1/50