Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) with an increasing incidence in developed countries. Recent reports suggest that modulation of the gut microbiota might be one promising therapy for MS. Here, we investigated whether the probiotic Escherich...

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Bibliographic Details
Main Authors: Thomas Secher, Sahar Kassem, Mehdi Benamar, Isabelle Bernard, Michele Boury, Frederick Barreau, Eric Oswald, Abdelhadi Saoudi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
Escherichia coli Nissle 1917
experimental autoimmune encephalomyelitis
probiotic
intestinal permeability
encephalitogenic T-cell
central nervous system
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01096/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01096/full

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