Porphyromonas gingivalis Induced Fragmentation of Type IV Collagen Through Macrophage-Activated MMP-9: (In Vitro Study of Collagenolytic Mechanism in Pathogenesis of Atherosclerotic Plaque Rupture)

BACKGROUND: Periodontitis is caused mostly by Porphyromonas gingivalis (P.gingivalis) and it is related to acute coronary syndrome. P.gingivalis  readily invades blood circulation and potentially induces collagenolytic activity of inflammatory cells that results in collagen vascular degradation lead...

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Bibliographic Details
Main Authors: Siti Nurul Mubarokah, I Dewa Agung Susilawati, Sumarno Sumarno, I Ketut Gedhe Muliartha, Djanggan Sargowo
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2009-12-01
Series:Indonesian Biomedical Journal
Online Access:http://inabj.org/index.php/ibj/article/view/105