Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice

Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice

We have previously reported that the activation of astrocytes and microglia may lead to the overproduction of proinflammatory mediators, which could induce neuroinflammation and cause brain edema in 1,2-dichloroethane (1,2-DCE)-intoxicated mice. In this research, we further hypothesized that astrocy...

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Bibliographic Details
Main Authors: Jinhan Yang, Tong Wang, Xiaoxia Jin, Gaoyang Wang, Fenghong Zhao, Yaping Jin
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
1,2-Dichloroethane poisoning
reactive astrocytes
microglial polarization
neuroinflammation
proinflammatory factors
brain edema formation
Online Access:https://www.mdpi.com/2073-4409/10/10/2647

Internet

https://www.mdpi.com/2073-4409/10/10/2647

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