Fatty acid synthase as a potential new therapeutic target for cervical cancer

Abstract Fatty acid synthase (FASN) is the rate-limiting enzyme for the de novo synthesis of fatty acids in the cytoplasm of tumour cells. Many tumour cells express high levels of FASN, and its expression is associated with a poorer prognosis. Cervical cancer is a major public health problem, repres...

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Main Authors: JÉSSICA NASCIMENTO, CAMILA MARIOT, DÉBORA R.B. VIANNA, LÚCIA M. KLIEMANN, PAULA S. CHAVES, MASSIMO LODA, ANDRÉIA BUFFON, RUY C.R. BECK, DIOGO A. PILGER
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2022-05-01
Series:Anais da Academia Brasileira de Ciências
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300705&lng=en&tlng=en