Isoliquiritigenin alleviates the development of alcoholic liver fibrosis by inhibiting ANXA2

Isoliquiritigenin alleviates the development of alcoholic liver fibrosis by inhibiting ANXA2

The study aimed to investigate the effect of isoliquiritigenin (ISL) on model of alcoholic liver fibrosis (ALF). C57BL/6 mice were used to establish animal model of ALF, HSC-T6 cells were used to establish alcohol-activated cell model, and tandem mass tag (TMT) assays were used to analyze the proteo...

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Bibliographic Details
Main Authors: Na Liu, Min Liu, Mengwei Jiang, Zhenwei Li, Weijun Chen, Wenxuan Wang, Xianglei Fu, Man Qi, MD HASAN ALI, Nan Zou, Qingguang Liu, Hui Tang, Shenghui Chu
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alcoholic liver fibrosis
Hepatic stellate cells
Annexin A2
Isoliquiritigenin
SPHKs/S1P/Th17 signaling
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222015621

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http://www.sciencedirect.com/science/article/pii/S0753332222015621

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