Receptor for Advanced Glycation End Product, Organ Crosstalk, and Pathomechanism Targets for Comprehensive Molecular Therapeutics in Diabetic Ischemic Stroke

Receptor for Advanced Glycation End Product, Organ Crosstalk, and Pathomechanism Targets for Comprehensive Molecular Therapeutics in Diabetic Ischemic Stroke

Diabetes mellitus, a well-established risk factor for stroke, is related to higher mortality and poorer outcomes following the stroke event. Advanced glycation end products(AGEs), their receptors RAGEs, other ligands, and several other processes contribute to the cerebrovascular pathomechanism inter...

Full description

Bibliographic Details
Main Authors: Nivedita L. Rao, Greeshma B. Kotian, Jeevan K. Shetty, Bhaskara P. Shelley, Mackwin Kenwood Dmello, Eric C. Lobo, Suchetha Padar Shankar, Shellette D. Almeida, Saiqa R. Shah
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
advanced glycation end products—AGEs
receptor for AGE (RAGE)
high-mobility group box 1 (HMGB1) nuclear protein
Leukotriene B4
pathomechanisms
diabetes mellitus
Online Access:https://www.mdpi.com/2218-273X/12/11/1712

Internet

https://www.mdpi.com/2218-273X/12/11/1712

Similar Items