Hypochlorite-induced oxidation promotes aggregation and reduces toxicity of amyloid beta 1-42

Hypochlorite-induced oxidation promotes aggregation and reduces toxicity of amyloid beta 1-42

Exacerbated hypochlorite (OCl−) production is linked to neurodegenerative processes, but there is growing evidence that lower levels of hypochlorite activity are important to protein homeostasis. In this study we characterise the effects of hypochlorite on the aggregation and toxicity of amyloid bet...

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Bibliographic Details
Main Authors: Noralyn B. Mañucat-Tan, Ashfaq Chowdhury, Rodrigo Cataldi, Rafaa Zeineddine Abdullah, Janet R. Kumita, Amy R. Wyatt
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Redox Biology
Subjects:
protein misfolding
Alzheimer's Disease
oxidative stress
Renewable energy
inflammation
post-translational modification
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723001374

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http://www.sciencedirect.com/science/article/pii/S2213231723001374

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