5-hydroxymethylcytosine is highly dynamic across human fetal brain development

Abstract Background Epigenetic processes play a key role in orchestrating transcriptional regulation during the development of the human central nervous system. We previously described dynamic changes in DNA methylation (5mC) occurring during human fetal brain development, but other epigenetic proce...

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Bibliographic Details
Main Authors: Helen Spiers, Eilis Hannon, Leonard C. Schalkwyk, Nicholas J. Bray, Jonathan Mill
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Genomics
Online Access:http://link.springer.com/article/10.1186/s12864-017-4091-x